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NPN: 80071979

Healthy mood balance.


  • High potency 400mg dose.
  • Helps support healthy liver function. 
  • Key factor in several important biological pathways.

30 tablets

I have [been using] this product for two weeks now. I have notice a marked difference in my mood. I feel more hopeful!! I have not noticed any side effects at all… It’s worth trying this natural product as opposed to using SSRI’s or any other type of antidepressant prescriptions. -James

Features Ingredients

SAMe is the amino acid, methionine, known to bind to ATP molecules that circulate in the blood acting as a “methyl” donor and known to boost the levels of the neurotransmitters serotonin, dopamine and norepinephrine.  SAMe is specifically designed to address the deficiency of these transmitters and contribute to its antidepressant action.

Organika’s SAMe is manufactured for maximum absorption using clear coated tablets, and 400mg per tablet to provide the highest potency.


RECOMMENDED USE OR PURPOSE: Helps relieve the symptoms and pain of osteoarthritis. Helps support healthy liver function. Helps support a healthy mood balance.

SAMe (S-Adenosyl-L-Methionine DisulfateTosylate) …………………….. 400 mg

NON-MEDICINAL INGREDIENTS: Microcrystalline Cellulose, Silica, Stearic Acid, Pregelatinized Starch.

Take 1 tablet three times per day. Avoid taking at bedtime.

Use for a minimum of 2 weeks to see beneficial effects.

CAUTIONS: Consult a health care practitioner if you are taking anti-depressants, hepatotoxic drugs or any other prescription medication; or if symptoms persist or worsen. Consult a health care practitioner prior to use if you have cardiovascular disease. Do not use if you are pregnant or breastfeeding; or if you have been diagnosed with bipolar disorder. Some people may experience anxiety, restlessness, insomnia, and/or a temporary increase in heart rate (tachycardia), in which case discontinue use. Flatulence, nausea, vomiting, diarrhea, constipation, dry mouth or headaches may occur.

CONTAINS NO: Dairy, egg, artificial preservatives, colours, yeast, artificial sweeteners, wheat, soya, gluten, or GMO ingredients.

SAMe has been recommended to ageing individuals not to just, feel better, but also to protect the brain, liver, joints and other tissues of the body like no other substance.