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PMS Relief
Hello, natural PMS relief
- Relieves premenstrual symptoms
- Supports more regular menstrual cycles by helping stabilize cycle irregularities
- Eases mild digestive disturbances and indigestion
- Calms restlessness or nervousness
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Supplement Facts
Ingredients & Nutrition
Medicinal: Lemon Balm 10:1 Extract (Melissa officinalis, Herb top) 300 mg (Equivalent to 3000 mg Dried Lemon Balm Herb Top powder), Chasteberry 10:1 Extract (Vitex agnus-castus, Fruit) 100 mg (Equivalent to 1000 mg Dried Chasteberry Fruit powder), Dong quai 10:1 Extract (Angelica sinensis, Root) 100 mg (Equivalent to 1000 mg Dried Dong quai Root powder), Vitamin B6 (Pyridoxine Hydrochloride) 20 mg.
Non-medicinal: Magnesium Stearate (Vegetable Source), Microcrystalline Cellulose, Hypromellose (Vegetarian Capsule).
Recommended Use: Adults only: Take 1 capsule, 1 time per day
Cautions: Ask a health care practitioner before use if you are taking hormone-containing medications such as progesterone preparations, oral contraceptives or hormone replacement therapy. Ask a health care practitioner before use if you have serious or major conditions, any type of acute infection, deficiency or excess. Ask a health care practitioner prior to use if you are taking any medications including blood thinners, birth control pills or hormone therapy. When using this product avoid exposure to the sun. When using this product, exercise caution if you drive or use machinery as you may experience drowsiness. Do not use if you are pregnant, breastfeeding or attempting to conceive unless you have consulted with a health care practitioner. Do not use if you have diarrhea, hemorrhagic diseases or heavy periods. Stop use and ask a health care practitioner if symptoms persist or worsen, or if new symptoms develop such as breast pain or any changes in menstrual cycles
Is This Right for You?
Are you dealing with premenstrual symptoms that disrupt your routine, like mood swings, irritability, cramps or breast tenderness?
Are you looking for natural PMS relief that also helps relieve restlessness or nervousness before your period?
Do you want support that helps stabilize menstrual cycle irregularities so your cycle feels more predictable?
Do you also get mild digestive disturbances or indigestion around your cycle and want one supplement that supports that too?
If you answered ''yes'' to any of the above, this product is right for you.
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Eases mild digestive disturbances and indigestion
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Calms restlessness or nervousness
Ingredients & Nutrition
Recommend For
Are you dealing with premenstrual symptoms that disrupt your routine, like mood swings, irritability, cramps or breast tenderness?
Are you looking for natural PMS relief that also helps relieve restlessness or nervousness before your period?
Do you want support that helps stabilize menstrual cycle irregularities so your cycle feels more predictable?
Do you also get mild digestive disturbances or indigestion around your cycle and want one supplement that supports that too?
If you answered ''yes'' to any of the above, this product is right for you.
Gluten-Free
Caffeine-Free
No Preservatives
Non-GMO
No Artificial Sweeteners
No Artificial Colours or Flavours
A daily supplement with chasteberry, dong quai, lemon balm and vitamin B6 that helps relieve premenstrual symptoms and support more regular cycles
Why we Made PMS Relief
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Eases mild digestive disturbances and indigestion
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Calms restlessness or nervousness
PMS Relief is a daily supplement made to support you through the days leading up to your period. It uses a synergistic blend of chasteberry, dong quai, lemon balm and vitamin B6 to help relieve premenstrual symptoms and make your cycle feel more manageable. PMS can show up as mood swings, cramps, breast tenderness, digestive discomfort or a restless irritability, and this formula is designed to support those common experiences.
Each ingredient plays a clear role in the body. Vitamin B6 helps ease mood swings and irritability. Chasteberry helps to reduce breast tenderness, support hormonal balance and contribute to the relief of premenstrual symptoms. Lemon balm helps relieve restlessness and nervousness so you feel calmer and more steady and dong quai, also known as angelica root, is traditionally used in herbal medicine to help relieve menstrual cramps and support menstrual flow. Together, these ingredients also help relieve mild digestive disturbances and indigestion, and help stabilize menstrual cycle irregularities so your cycle feels more predictable over time.
Take PMS Relief daily, ideally starting 1 to 2 weeks before your period and continuing through your cycle. Use it consistently for a few cycles so you can properly track changes in your symptoms. PMS Relief is a good fit if you want natural PMS relief and support for menstrual cycle irregularities, especially if your PMS affects mood, digestion, sleep or comfort.
Ask Away
We’ve got the FAQs covered. But if you’re still stuck, we’re only a message away.
Get in TouchHow long should I take it before seeing results?
The recommendation is to use for at least 3 months to see beneficial effects
Do I need to take it every day or only during my period?
It is recommended to take 1 capsule a day, as per taking it only during your period, it is up to the users discretion, but it is not recommended to be used when you have heavy periods.
Why does this formula include Vitamin B6?
Vitamin B6 helps with energy metabolism/tissue formation as well as forming red blood cells. It can help stabilize mood, support hormone balance, and aid in blood health for someone who may have heavy periods.
Are there any possible side effects?
When using this product, avoid exposure to the sun as well as exercise caution if you drive or use machinery as you may experience drowsiness. Stop use if you develop new symptoms such as breast pain or any changes in menstrual cycles
Can I take this with other medications?
It is best to ask a health care practitioner before use if you are taking hormone containing medications, oral contraceptives, or hormone replacement therapy
When should I stop using PMS Relief and consult a healthcare practitioner?
If symptoms worsen or if you develop new symptoms such as breast pain or any changes in menstrual cycles.
Is this product suitable for long-term use?
At least three months is the recommended usage, however for longer term usage, it is up to the user but ask a health care practitioner first.
Can I take more than one capsule per day?
Our dosages are designed for one capsule per day. If taken more per day, we recommend asking a health care practitioner.
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Support Beyond Products
Magnesium's Role in Supporting the Health of Postmenopausal Women Magnesium plays a crucial role in supporting the health of postmenopausal women, especially in maintaining bone density, cardiovascular health, and metabolic function. As estrogen levels drop after menopause, women face an increased risk of osteoporosis and cardiovascular issues. Magnesium's Role in Bone Health Magnesium is vital in bone formation as it regulates calcium and vitamin D, helping to preserve bone strength. Research has shown that postmenopausal women often have lower serum magnesium levels, which are associated with a higher risk of osteoporosis and bone-related issues (Kumar et al., 2016). Supplementing with magnesium may help reduce the negative effects of bone density loss. Supporting Cardiovascular Health with Magnesium Additionally, magnesium is essential for heart health. A study found that dietary magnesium restriction in postmenopausal women led to heart rhythm changes and impaired glucose tolerance (Nielsen et al., 2007). Another study revealed that postmenopausal women have significantly lower serum calcium and magnesium levels compared to premenopausal women, emphasizing the need for magnesium supplementation to support cardiovascular health (Vani, 2023). Pairing an Organika magnesium with Organika’s Enhanced Collagen Bone & Joint is a fabulous combination to keep postmenopausal women’s bone strength. There is also added Vitamins D3 + K2 that helps drive the calcium in the bones. Magnesium and Metabolic Function Magnesium also helps regulate insulin sensitivity, which is key for metabolic health. In healthy postmenopausal women, low magnesium levels were linked to insulin resistance, further underscoring the need for proper magnesium intake (Laires et al., 2004). Recommended Daily Magnesium Intake for Postmenopausal Women Postmenopausal women should aim for the recommended daily allowance (RDA) of around 320 mg of magnesium. 200 mg can be found in just one Organika capsule of Magnesium Bisglycinate. Consuming magnesium-rich foods like leafy greens, nuts, seeds, and whole grains can help maintain adequate levels, but supplements may be necessary for those struggling to meet their needs. Proper magnesium intake is essential for postmenopausal women, as it supports bone health, reduces cardiovascular risks, and improves metabolic function. Always consult with a healthcare provider before adding magnesium supplements to your routine to ensure the appropriate dosage based on individual health conditions.
read moreProtein is an essential macronutrient for everyone, but for women, meeting daily protein needs takes on special significance across every stage of life. From supporting hormonal balance during reproductive years to preserving muscle mass through menopause and beyond, protein plays irreplaceable roles in maintaining health, energy, and vitality. Yet research consistently shows that many women fall short of optimal protein intake, often without realizing the impact on their well-being. Whether you're navigating the demands of an active lifestyle, balancing the nutritional needs of a growing family alongside your own, experiencing hormonal transitions, or focused on maintaining strength and independence with age, understanding how protein supports your unique needs can be transformative. Here's why prioritizing protein is essential to daily vitality. Preserves Muscle Mass and Strength Throughout Life Muscle health matters at every age, but women face unique challenges when it comes to maintaining muscle mass. Starting around age 30, adults naturally begin losing muscle mass at a rate of 3-8% per decade, with this decline accelerating significantly after age 65. For women, hormonal changes during perimenopause and menopause can intensify this muscle loss, making adequate protein intake even more critical. Protein serves as the fundamental building block for muscle tissue. When we consume protein-rich foods, the body breaks them down into molecular components that rebuild and repair muscle fibers known as amino acids. . This process of muscle protein synthesis happens continuously, but research shows that older adults, particularly postmenopausal women, experience "anabolic resistance" which is a reduced ability to build muscle in response to protein intake. This means that women need more protein as they age, not less. Studies indicate that women should aim for 1.2 g/kg body weight per day—significantly more than the standard 0.8 g/kg recommendation — to effectively preserve muscle mass and enhance strength, particularly after age 50. For a woman weighing 70 kg (154 lbs.), this translates to approximately 84 grams of protein daily. Research shows this higher intake leads to notable improvements in muscle composition, reduced fat accumulation, and better overall physical function. Active women in their 20s and 30s also benefit from adequate protein intake, particularly when engaging in regular exercise. Protein supports muscle recovery and adaptation to training, helping maintain lean muscle mass that supports metabolism and functional strength for decades to come. Supports Hormonal Health and Balance Hormones orchestrate virtually every aspect of female health, from menstrual cycles and fertility to mood regulation and metabolism. Hormones are made from proteins that rely on amino acids for their production and function. Without adequate protein intake, the body lacks the building blocks needed to maintain hormonal balance. Protein plays a particularly vital role during perimenopause and menopause, when hormonal fluctuations can trigger a cascade of physical and emotional changes. It can help build muscles more effectively and mitigate some menopausal symptoms. The decline in estrogen during menopause affects muscle protein synthesis, making this strategic protein timing especially important. Beyond structural hormones, amino acids serve as precursors to neurotransmitters that regulate mood and emotional well-being. Tryptophan, an amino acid that contributes to maintenance of muscles, enzymes and neurotransmitters, converts to serotonin (influencing feelings of well-being and happiness), while tyrosine, one of the 20 standard amino acids cells use to synthetize proteins, becomes dopamine (critical for motivation and learning). Adequate protein intake helps stabilize blood sugar levels, preventing the dramatic fluctuations that can trigger mood swings, anxiety, and difficulty concentrating. Intriguingly, research has found that higher vegetable protein intake may actually support reproductive longevity. A large study of over 85,000 women found that those consuming the highest amounts of vegetable protein had a 16% lower risk of early menopause (before age 45) compared to those with the lowest intake, suggesting that plant-based proteins may help prolong female reproductive function. Enhances Weight Management and Metabolic Health For women navigating weight management, protein offers distinct advantages. Its remarkable satiating effect helps promote feelings of fullness for extended periods, naturally reducing overall calorie intake without the constant struggle of hunger. The science behind this is compelling: protein increases appetite-suppressing hormones more effectively than carbohydrates or fats and requires more energy to digest — a phenomenon called the thermic effect of food. This means the body actually burns more calories processing protein compared to other macronutrients, providing a modest but meaningful metabolic advantage. During perimenopause and menopause, many women experience frustrating weight gain, particularly around the abdomen. Emerging research suggests this may be partly due to the body's increased appetite for protein during hormonal transitions. When protein needs aren't met, women may unconsciously overconsume other forms of energy (carbohydrates and fats) to compensate. Studies suggest that increasing the proportion of protein in the diet by around 3% of daily energy intake, whilst slightly reducing overall energy intake by 5-10%, may help prevent or lessen perimenopausal weight gain. Strengthens Bones and Reduces Osteoporosis Risk While calcium and vitamin D rightfully receive attention for bone health, protein's critical role is often overlooked. Our bones are made up of a significant amount of protein—about 30%. Structural protein provides the framework upon which minerals are deposited, creating the strength and resilience that bones need to withstand daily stresses. For women, bone health becomes increasingly critical after menopause, when declining estrogen levels accelerate bone loss. Women can lose up to 20% of bone mass during the perimenopausal transition and the few years following menopause, dramatically increasing the risk of osteoporosis and fractures. This makes adequate protein intake essential for preserving bone density. Research consistently demonstrates that higher protein intake is associated with better bone mineral density, slower rates of bone loss, and reduced fracture risk in postmenopausal women. Studies show that protein intake above 0.8 g/kg body weight daily, combined with calcium intake of at least 800 mg/day, can reduce hip fracture risk by up to 85%. Conversely, this protective effect may be reversed with insufficient calcium, highlighting the importance of balanced nutrition. Supports Maternal Health During Pregnancy and Breastfeeding During pregnancy, protein needs increase progressively, with the most significant increases occurring in the second and third trimesters. Current recommendations suggest a minimum of 75 grams daily during pregnancy (compared to 46 grams for non-pregnant women), with some research showing that even that may be too low. This additional protein supports the development of fetal tissues, the expansion of maternal blood volume, growth of breast and uterine tissue and preparation for lactation. Meeting protein needs during pregnancy is crucial for maternal health too. Insufficient protein increases the risk of developing anemia, poor maternal weight gain, complications during delivery, and adverse pregnancy outcomes including preterm birth and low birth weight. During lactation, the story becomes even more compelling. The current dietary recommendation suggests 1.05 g/kg body weight daily for breastfeeding women. However, groundbreaking research has revealed that exclusively breastfeeding women actually need 1.7-1.9 g/kg daily—substantially higher than current guidelines. For a 70 kg woman, this means approximately 119-133 grams of protein daily, compared to the currently recommended 74 grams. This higher protein requirement makes sense when we consider the demands of lactation: women must maintain their own muscle mass whilst providing all the nutrients an infant needs through breast milk. Adequate protein supports tissue repair after childbirth, helps maintain energy levels during the demanding postpartum period, and ensures optimal milk composition for infant growth and development. Promotes Vibrant Skin, Hair, and Nail Health Visible markers of health and vitality like radiant skin, strong nails , and lustrous hair, all depend fundamentally on adequate protein intake. These tissues are primarily composed of structural proteins including collagen, keratin, and elastin. Collagen provides skin with its firmness and resilience, keratin forms the structure of hair and nails, and elastin allows skin to stretch and return to its original shape. As women age, natural collagen production declines, contributing to visible signs of ageing like wrinkles, thinning skin, and brittle nails. Many women also notice hair loss or thinning during menopause. Collagen supplementation may help by providing essential amino acids that build keratin, the hair's primary protein, whilst also supporting healthy hair follicles and helping prevent age-related thinning. Maintaining adequate protein intake —and specifically ensuring sufficient amino acids needed for collagen synthesis, —helps preserve the structural integrity of these tissues. High-quality protein sources provide the building blocks necessary to maintain healthy, vibrant skin, hair, and nails throughout all stages of life. How Much Protein Do Women Really Need? Protein requirements for women aren't one-size-fits-all and can vary based on age, activity level, life stage, and health status. While the baseline recommendation of 0.8 g/kg body weight daily prevents deficiency, emerging research suggests this may not be optimal for many women, particularly as they age or during periods of increased physiological demand. For most adult women: Many nutrition experts now recommend 1.0-1.2 g/kg body weight daily to better support muscle maintenance, metabolic health, and overall well-being. For a 65 kg (143 lb.) woman, this translates to 65-78 grams of protein daily. For active women: Those engaging in regular exercise, particularly strength training or endurance activities, benefit from 1.2-1.7 g/kg daily to support muscle recovery, adaptation, and performance. For women over 50: To combat anabolic resistance and preserve muscle mass, 1.2-1.5 g/kg daily is recommended, with some research suggesting needs may be even higher for those with sarcopenia or recovering from illness. During pregnancy: A minimum of 60 grams daily, with many experts recommending at least 75-100 grams for optimal maternal and fetal health. During breastfeeding: Current research suggests 1.7-1.9 g/kg daily for exclusively breastfeeding women, significantly higher than older recommendations. Protein Distribution Matters Too Beyond total daily intake, research increasingly emphasizes the importance of distributing protein throughout the day rather than consuming most of it at one meal. To maximize muscle protein synthesis aim to include 25-30 grams of high-quality protein at each main meal. For women in perimenopause and menopause, there's growing evidence that consuming 30-50 grams of protein at breakfast or the first meal of the day may be particularly effective for building muscle. This strategic timing works with the body's changing hormonal environment to support muscle protein synthesis more effectively. Choosing High-Quality Protein Sources The quality of protein matters just as much as quantity. Focus on nutrient-dense sources that provide not just protein, but also vitamins, minerals, and other beneficial compounds that support overall health. Whilst red meat can be part of a balanced diet, research consistently shows it should be consumed in moderation. Studies link higher consumption of red meat—especially processed varieties—to increased risks of cardiovascular disease, type 2 diabetes, and certain cancers. The evidence is clear: replacing some red meat with plant-based proteins, fish, or poultry reduces these health risks whilst still meeting protein needs. Practical Strategies for Meeting Protein Goals Meeting daily protein targets doesn't require complicated meal planning. Here are some straightforward strategies: Start the day with protein-rich options like eggs, Greek yogurt, or a protein smoothie to stabilize blood sugar and energy levels Include a palm-sized portion of protein at each main meal—roughly 25-30 grams per serving Keep convenient protein-rich snacks available: nuts, cheese, Greek yogurt, or hard-boiled eggs Add protein to familiar foods: stir Greek yogurt into porridge, add beans to salads and soups, include nuts in grain dishes Plan meals intentionally to ensure a balance of protein, healthy fats, and carbohydrates throughout the day For busy mothers preparing family meals, batch-cook protein sources like grilled chicken, boiled eggs, or cooked legumes to have ready throughout the week Making Protein a Priority Incorporating adequate, high-quality protein into your diet can lead to significant health benefits throughout a woman's life. The key is to consume enough protein throughout the day from diverse, nutrient-dense sources that align with individual needs and preferences. When getting adequate protein intake becomes complicated, protein powders and supplements can help bridge the gap. They offer a convenient way to meet daily protein goals alongside whole food sources, particularly during demanding life stages like breastfeeding or whilst managing the increased needs of perimenopause and menopause. CTA: Find your protein References & Further Reading Frontiers in Nutrition. (2025). "Role of protein intake in maintaining muscle mass composition among elderly females suffering from sarcopenia." https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1547325/full Harvard Health Publishing. (2024). "Muscle loss and protein needs in older adults." https://www.health.harvard.edu/staying-healthy/muscle-loss-and-protein-needs-in-older-adults Cleveland Clinic. (2025). "How Much Protein You Need." https://health.clevelandclinic.org/how-much-protein-you-need National Institutes of Health. "Dietary protein recommendations and the prevention of sarcopenia." https://pmc.ncbi.nlm.nih.gov/articles/PMC2760315/ Harvard T.H. Chan School of Public Health. "Protein." https://nutritionsource.hsph.harvard.edu/what-should-you-eat/protein/ Current Developments in Nutrition. (2020). "Protein Requirements of Healthy Lactating Women Are Higher Than the Current Recommendations." https://pmc.ncbi.nlm.nih.gov/articles/PMC7257931/ UCSF Health. (2024). "Eating Right Before and During Pregnancy." https://www.ucsfhealth.org/education/eating-right-before-and-during-pregnancy American Pregnancy Association. (2024). "Pregnancy Nutrition." https://americanpregnancy.org/healthy-pregnancy/pregnancy-health-wellness/pregnancy-nutrition/ PMC. (2016). "Nutrition Recommendations in Pregnancy and Lactation." https://pmc.ncbi.nlm.nih.gov/articles/PMC5104202/ University of Sydney. (2022). "Prioritising protein during perimenopause may ward off weight gain." https://www.sydney.edu.au/news-opinion/news/2022/10/13/prioritising-protein-during-perimenopause-may-ward-off-weight-gain.html Elektra Health. (2023). "Protein During Menopause: How Much Do We Really Need?" https://www.elektrahealth.com/blog/protein-during-menopause/ MDPI Nutrients. (2024). "The Impact of Protein in Post-Menopausal Women on Muscle Mass and Strength." https://www.mdpi.com/2673-9488/4/3/16 Bonafide. (2025). "Protein for Menopause." https://hellobonafide.com/blogs/news/why-protein-is-essential-during-menopause PMC. (2018). "Dietary Protein Intake and Early Menopause in the Nurses' Health Study II." https://pmc.ncbi.nlm.nih.gov/articles/PMC5860152/ PMC. (2014). "Dietary protein is beneficial to bone health under conditions of adequate calcium intake." https://pmc.ncbi.nlm.nih.gov/articles/PMC4180248/ International Osteoporosis Foundation. (2025). "Protein and other nutrients." https://www.osteoporosis.foundation/health-professionals/prevention/nutrition/protein-and-other-nutrients Nature Scientific Reports. (2025). "Association between dietary protein intake and bone mineral density." https://www.nature.com/articles/s41598-025-93642-w WebMD. "The Benefits of Protein." https://www.webmd.com/diet/benefits-protein
read moreAre you a recent or soon-to-be mom and interested in supplementing with collagen? Your body goes through many changes as you enter motherhood. Learn about how your body can benefit from collagen while breastfeeding and over the course of pregnancy, and make an informed choice! First of all, what's collagen? Collagen is a protein made up primarily of the amino acids glycine, proline and hydroxyproline (1). It is the most abundant protein in the human body, as it is a major building block of all connective and fibrous tissue, eg: hair, skin, bone, cartilage, tendons, ligaments, blood vessels and the fibrous structure of organs (2). Research shows collagen supplementation is beneficial for a variety of conditions. This includes: Joint pain Osteoarthritis Rheumatoid arthritis Brittle nails Cellulite Skin health It is possibly also useful in preventing or treating conditions such as sun-damaged skin, exercise-induced injury, hypertension, type II diabetes, and osteoporosis. New research is also exploring collagen’s possible utility in repairing the stomach and intestinal walls in cases of digestive inflammation or “leaky gut”. How does the body use collagen while breastfeeding or pregnant? Nutrition requirements change during pregnancy and breastfeeding due to the needs of the fetus and newborn infants. In particular, the demand for amino acids and protein significantly increases (3). Inadequate protein intake during this period can have negative impacts on the short and long-term health of mother and child. Because studies on pregnant or breastfeeding individuals are generally not permitted, there has been no direct investigation into the use of collagen while breastfeeding and during pregnancy. However, collagen is a naturally occurring substance found in animal products, made up of amino acids, which our bodies are very familiar with utilizing. Generally, collagen supplements at reasonable doses are considered to be safe and without side effects (4,5). If you have an allergy to fish or seafood, avoid marine-sourced collagen. Instead, choose products sourced from bovine, poultry or eggshell sources (6). Here's the bottom line: While we can’t say for certain how the body utilizes collagen while breastfeeding and during pregnancy, collagen is a great source of amino acids and protein. It is also very easily absorbed, even in those with challenged digestive systems. Combined with its utility in improving and maintaining health in a number of areas, this makes regular collagen supplementation a great source for additional amino acids and protein during pregnancy and breastfeeding. References Silvipriya, K., Kumar, K., Bhat, A., Kumar, B., John, A., & Lakshmanan, P. (2015). Collagen: Animal sources and biomedical application. Journal of Applied Pharmaceutical Science,5(3), 123-127. Sibilla, S., Godfrey, M., Brewer, S., Budh-Raja, A., & Genovese, L. (2015). An overview of the beneficial effects of hydrolyzed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. The Open Nutraceuticals Journal,8(1), 29-42. Elango, R., and Ball, R.O. (2016). Protein and amino acid requirements during pregnancy. Advances in Nutrition, 7(4), 839S-844S. Choi, F. D., Sung, C. T., Juhasz, M. L., & Mesinkovsk, N. A. (2019). Oral collagen supplementation: A systematic review of dermatological applications. Journal of Drugs in Dermatology,18(1), 9-16. Liu, X., Machado, G., Eyles, J., Ravi, V., & Hunter, D. (2018). Dietary supplements for treating osteoarthritis: A systematic review and meta-analysis. British Journal of Sports Medicine,52, 1-10. Ruff, K. J., Winkler, A., Jackson, R. W., Devore, D. P., & Ritz, B. W. (2009). Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: A randomized, multicenter, double-blind, placebo-controlled clinical study. Clinical Rheumatology,28(8), 907-914.
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